Product Certification&
    Enterprise Certification

  • Mr.Ronghu Chen
    Tel: 86-838-2274206

  • Mobile:18280587216
  • Tel:86-838-2274206
  • Fax:86-838-2274207
  • URL:http://www.aminoacid.cc
  • Province/state:sichuan
  • City:deyang
  • Street:Room 1-11-1,No.19 of North TianShan Road,Deyang,Sichuan China
  • MaxCard:
Home > Products >  Vildagliptin 274901-16-5

Vildagliptin 274901-16-5 CAS NO.274901-16-5

  • Min.Order: 0 Metric Ton
  • Payment Terms: L/C
  • Product Details

Keywords

  • pyrrolidine-2-carbonitrile
  • Hydroxytricyclo
  • 274901-16-5

Quick Details

  • ProName: Vildagliptin 274901-16-5
  • CasNo: 274901-16-5
  • Molecular Formula: C17H25N3O2
  • Application: drug intermidiate
  • ProductionCapacity: Metric Ton/Day
  • Purity: 99.85%
  • LimitNum: 0 Metric Ton

Superiority

Name: Vildagliptin 
CAS No.: 274901-16-5 
MF: C17H25N3O2 
Use: Anti-diabetic agent 
Appearance: White powder 

General introduction: Vildagliptin (previously identified as LAF237, trade name ZOMELIS) is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin inhibits the inactivation of GLP-1 and GIPby DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas. 
Vildagliptin has been shown to reduce hyperglycemia in type 2 diabetes mellitus. 
The Food and Drug Administration had demanded additional clinical data before it could approve vildagliptin including extra evidence that skin lesions and kidney impairment seen during an early study on animals have not occurred in human trials. 
Packaging & Delivery 

Packaging Detail: Accoring to your requirement 
Delivery Detail: Prompt

 


Appearance
 

White crystalline powder
 

Conforms
 

Identification
 

IR/HPLC
 

Conforms
 

Melting point
 

148.0-150.0°C
 

148.5-149.2°C
 

Loss on drying
 

≤ 1.0%
 

0.18%
 

Residue on ignition
 

≤ 0.1%
 

0.05%
 

Heavy metals
 

≤20ppm
 

Conforms
 

Sulphate
 

≤ 0.02%
 

Conforms
 

Chloride
 

≤ 0.05%
 

Conforms
 

Ethyl acetate
 

≤ 0.5%
 

0.11%
 

Related impurity
 

Single impurity≤ 0.5%
Total impurities≤ 1.0%
 

0.15%
Conforms
 

Purity
 

≥99.0%
 

99.85%

 

Details


Appearance
 

White crystalline powder
 

Conforms
 

Identification
 

IR/HPLC
 

Conforms
 

Melting point
 

148.0-150.0°C
 

148.5-149.2°C
 

Loss on drying
 

≤ 1.0%
 

0.18%
 

Residue on ignition
 

≤ 0.1%
 

0.05%
 

Heavy metals
 

≤20ppm
 

Conforms
 

Sulphate
 

≤ 0.02%
 

Conforms
 

Chloride
 

≤ 0.05%
 

Conforms
 

Ethyl acetate
 

≤ 0.5%
 

0.11%
 

Related impurity
 

Single impurity≤ 0.5%
Total impurities≤ 1.0%
 

0.15%
Conforms
 

Purity
 

≥99.0%
 

99.85%

 

Other products of this supplier

lookchemhot product CAS New CAS